منابع مشابه
Voltage Sensor
The Tokamak Physics Experiment (TPX) was a steady-state, tokamak to be built at the Princeton Plasma Physics Laboratory. It would have been the first tokamak in the world with an entirely superconducting magnet system. The project was terminated by the United States Congress in 1995. However, most of the TPX mission has been adopted recently by the South Korean project KSTAR (Korean Superconduc...
متن کاملQuartet Compatibility and the Quartet Graph
A collection P of phylogenetic trees is compatible if there exists a single phylogenetic tree that displays each of the trees in P. Despite its computational difficulty, determining the compatibility of P is a fundamental task in evolutionary biology. Characterizations in terms of chordal graphs have been previously given for this problem as well as for the closely-related problems of (i) deter...
متن کاملThe voltage sensor in voltage-dependent ion channels.
In voltage-dependent Na, K, or Ca channels, the probability of opening is modified by the membrane potential. This is achieved through a voltage sensor that detects the voltage and transfers its energy to the pore to control its gate. We present here the theoretical basis of the energy coupling between the electric field and the voltage, which allows the interpretation of the gating charge that...
متن کاملVoltage Sensor Movements
The voltage dependence of K , Na , and Ca 2 channels is brought about by a voltage sensor that moves 12–13 e 0 across the entire electric field (Schoppa et al., 1992; Hirschberg et al., 1996; Noceti et al., 1996). In the case of Shaker K channel it is known which residues are responsible for this large amount of gating charge. This was found by measuring the total gating charge movement per cha...
متن کاملThe voltage sensor module in sodium channels.
The mechanism by which voltage-gated ion channels respond to changes in membrane polarization during action potential signaling in excitable cells has been the subject of research attention since the original description of voltage-dependent sodium and potassium flux in the squid giant axon. The cloning of ion channel genes and the identification of point mutations associated with channelopathy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2008
ISSN: 0028-0836,1476-4687
DOI: 10.1038/456183a